MACI is the current evolution of the technique Autologous Chondrocyte Implantation (ACI) initially developed in 1994.

Once the decision is made to consider MACI, there are several steps:

  • Your surgeon will perform a diagnostic knee arthroscopy and obtain tiny cartilage biopsies.
  • Vericel receives the cartilage cells (chondrocytes) and begins the cell culture process, expanding them and placing them onto a collagen membrane. (This process usually takes 4-6 weeks.)
  • Your surgeon implants the MACI membrane, also correcting any other issues at the same time, such as ligament reconstruction or osteotomy.
  • Once implanted, your cells begin to create cartilage repair tissue to regenerate the areas of the defects.
  • A customized physical therapy program, incorporating home use of continuous passive motion CPM device, will facilitate your recovery process.

Tibiofemoral Defects – Rehabilitation Guide.pdf
Patellofemoral Defects – Rehabilitation Guide.pdf
MACI Process and Cartilage Fill One Pager (DIGITAL).pdf
MACI Manufacturing Overview.pdf

MACI video for patients

COVID-19 Update

As the Coronavirus situation remains ever-changing, the safety of our patients and employees remains our top priority.

  • We have returned to normal business hours and are currently seeing patients in our office for ALL orthopaedic medical appointments as well as Physical & Occupational Therapy appointments. 
  • We are still offering Televisits as an option for your care.
  • We want to assure you we are maintaining strict safety guidelines in regard to sanitation of our office and social distancing guidelines as outlined by the MA Dept. of Public Health and the CDC. Please read this updated letter to our patients for further details.

We will continue to provide updates on our website and on our Facebook page. Thank you for your patience, trust and understanding during this challenging time. Be well and stay safe!